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Second hit determines immune response against developing Burkitts lymphoma
The human c-myc gene encodes a transcription factor (MYC) involved in the regulation of a vast number of other genes - it has been estimated that the transcription of about one in six genes is somehow under the control of MYC.
From: http://www.news-medical.net/news/20111109/Second-hit-determines-immune-response-against-developing-Burkitts-lymphoma.aspx
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How Major Signaling Pathways Are Wired to Our Genome Gives New Insight Into Disease Processes
Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. By manipulating these pathways, scientists may find new ways to treat cancer and other diseases.
From: http://www.newswise.com/articles/view/582042/?sc=rssn
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